Dr Chris Brosnan
Research Fellow/Senior Research officer
Queensland Alliance for Agriculture and Food Innovation
Affiliate of ARC Research Hub for Sustainable Crop Protection
ARC Research Hub for Sustainable Crop Protection
Book Chapter
Brosnan, C.A., McCallum,E.J., Botella, J.R. and Carroll, B.J. (2008). RNA Interference. The Handbook of Plant Functional Genomics: Concepts and Protocols. (pp. 209-225) edited by Kahl, G. and Meksem, K.. Germany: Wiley - Blackwell. doi: 10.1002/9783527622542.ch10
Journal Articles
Fletcher, Stephen J., Lawrence, Jai, Sawyer, Anne, Manzie, Narelle, Gardiner, Donald M., Mitter, Neena and Brosnan, Christopher A. (2025). dsRNAmax: a multi-target chimeric dsRNA designer for safe and effective crop protection. NAR Genomics and Bioinformatics, 7 (2) lqaf064, lqaf064. doi: 10.1093/nargab/lqaf064
Yong, Jiaxi, Xu, Wang, Wu, Miaomiao, Zhang, Run, Mann, Christopher W. G., Liu, Guoquan, Brosnan, Christopher A., Mitter, Neena, Carroll, Bernard J. and Xu, Zhi Ping (2025). Lysozyme-coated nanoparticles for active uptake and delivery of synthetic RNA and plasmid-encoded genes in plants. Nature Plants, 11 (1) e2106945, 131-144. doi: 10.1038/s41477-024-01882-x
Tsai, Wei-An, Brosnan, Christopher A., Mitter, Neena and Dietzgen, Ralf G. (2024). Involvement of MicroRNAs in the hypersensitive response of capsicum plants to the capsicum chlorosis virus at elevated temperatures. Pathogens, 13 (9) 745. doi: 10.3390/pathogens13090745
Devers, Emanuel A., Brosnan, Christopher A., Sarazin, Alexis, Schott, Gregory, Lim, Peiqi, Lehesranta, Satu, Helariutta, Yrjö and Voinnet, Olivier (2023). In planta dynamics, transport‐biases, and endogenous functions of mobile siRNAs in Arabidopsis. The Plant Journal, 115 (5), 1377-1393. doi: 10.1111/tpj.16327
Dai, Chuan-Yang, Ng, Chai Chee, Hung, Grace Ching Ching, Kirmes, Ina, Hughes, Laetitia A., Du, Yunguang, Brosnan, Christopher A., Ahier, Arnaud, Hahn, Anne, Haynes, Cole M., Rackham, Oliver, Filipovska, Aleksandra and Zuryn, Steven (2023). ATFS-1 counteracts mitochondrial DNA damage by promoting repair over transcription. Nature Cell Biology, 25 (8), 1-10. doi: 10.1038/s41556-023-01192-y
Tsai, Wei-An, Brosnan, Christopher A., Mitter, Neena and Dietzgen, Ralf G. (2022). Perspectives on plant virus diseases in a climate change scenario of elevated temperatures. Stress Biology, 2 (1) 37, 1-26. doi: 10.1007/s44154-022-00058-x
Hoang, Bao Tram L., Fletcher, Stephen J., Brosnan, Christopher A., Ghodke, Amol B., Manzie, Narelle and Mitter, Neena (2022). RNAi as a foliar spray: efficiency and challenges to field applications. International Journal of Molecular Sciences, 23 (12) 6639, 6639. doi: 10.3390/ijms23126639
Jain, Ritesh G, Fletcher, Stephen J, Manzie, Narelle, Robinson, Karl E, Li, Peng, Lu, Elvin, Brosnan, Christopher A, Xu, Zhi Ping and Mitter, Neena (2022). Foliar application of clay-delivered RNA interference for whitefly control. Nature Plants, 8 (5), 535-548. doi: 10.1038/s41477-022-01152-8
Brosnan, Christopher A. and Mitter, Neena (2021). miRNA communication on another level. Nature Plants, 7 (10), 1328-1329. doi: 10.1038/s41477-021-01006-9
Richman, Tara R., Ermer, Judith A., Siira, Stefan J., Kuznetsova, Irina, Brosnan, Christopher A., Rossetti, Giulia, Baker, Jessica, Perks, Kara L., Cserne Szappanos, Henrietta, Viola, Helena M., Gray, Nicola, Larance, Mark, Hool, Livia C., Zuryn, Steven, Rackham, Oliver and Filipovska, Aleksandra (2021). Mitochondrial mistranslation modulated by metabolic stress causes cardiovascular disease and reduced lifespan. Aging Cell, 20 (7) e13408, e13408. doi: 10.1111/acel.13408
Lee, Chin Hong, Hawker, Nathaniel P., Peters, Jonathan R., Lonhienne, Thierry G. A., Gursanscky, Nial R., Matthew, Louisa, Brosnan, Christopher A., Mann, Christopher W. G., Cromer, Laurence, Taochy, Christelle, Ngo, Quy A., Sundaresan, Venkatesan, Schenk, Peer M., Kobe, Bostjan, Borges, Filipe, Mercier, Raphael, Bowman, John L. and Carroll, Bernard J. (2021). Defective embryo and meristems genes are required for cell division and gamete viability in Arabidopsis. PL o S Genetics, 17 (5) e1009561, 1-31. doi: 10.1371/journal.pgen.1009561
Brosnan, Christopher A., Palmer, Alexander J. and Zuryn, Steven (2021). Cell-type-specific profiling of loaded miRNAs from Caenorhabditis elegans reveals spatial and temporal flexibility in Argonaute loading. Nature Communications, 12 (1) 2194, 1-16. doi: 10.1038/s41467-021-22503-7
Moro, Belén, Kisielow, Malgorzata, Borrero, Veronica Barragan, Bouet, Antoine, Brosnan, Christopher A. and Bologna, Nicolás G. (2021). Nuclear RNA purification by flow cytometry to study nuclear processes in plants. STAR Protocols, 2 (1) 100320, 100320. doi: 10.1016/j.xpro.2021.100320
Devers, Emanuel A., Brosnan, Christopher A., Sarazin, Alexis, Albertini, Daniele, Amsler, Andrea C., Brioudes, Florian, Jullien, Pauline E., Lim, Peiqi, Schott, Gregory and Voinnet, Olivier (2020). Movement and differential consumption of short interfering RNA duplexes underlie mobile RNA interference. Nature Plants, 6 (7), 789-799. doi: 10.1038/s41477-020-0687-2
Brosnan, Christopher Andrew, Sarazin, Alexis, Lim, PeiQi, Bologna, Nicolas Gerardo, Hirsch-Hoffmann, Matthias and Voinnet, Olivier (2019). Genome-scale, single-cell-type resolution of microRNA activities within a whole plant organ. EMBO Journal, 38 (13) e100754, e100754. doi: 10.15252/embj.2018100754
Iki, Taichiro, Clery, Antoine, Bologna, Nicolas G., Sarazin, Alexis, Brosnan, Christopher A., Pumplin, Nathan, Allain, Frederic H. T. and Voinnet, Olivier (2018). Structural flexibility enables alternative maturation, ARGONAUTE sorting and activities of miR168, a global gene silencing regulator in plants. Molecular Plant, 11 (8), 1008-1023. doi: 10.1016/j.molp.2018.05.006
Tschopp, Marie-Aude, Iki, Taichiro, Brosnan, Christopher A., Jullien, Pauline E. and Pumplin, Nathan (2017). A complex of Arabidopsis DRB proteins can impair dsRNA processing. RNA, 23 (5), 782-797. doi: 10.1261/rna.059519.116
Christie, Michael, Brosnan, Christopher A., Rothnagel, Joseph A. and Carroll, Bernard J. (2011). RNA decay and RNA silencing in plants: Competition or collaboration?. Frontiers in Plant Science, 2 (DEC) 99, 99.1-99.7. doi: 10.3389/fpls.2011.00099
Brosnan, Christopher Andrew and Voinnet, Olivier (2011) Cell-to-cell and long-distance siRNA movement in plants: Mechanisms and biological implications. Current Opinion in Plant Biology, 14 5: 580-587. doi:10.1016/j.pbi.2011.07.011
Brosnan, Christopher A. and Voinnet, Olivier (2009) The long and the short of noncoding RNAs. Current Opinion in Cell Biology, 21 3: 416-425. doi:10.1016/j.ceb.2009.04.001
Brosnan, C., Mitter, N., Christie, M., Smith, N., Waterhouse, P. and Carroll, B. (2007). Nuclear gene silencing directs reception of long-distance mRNA silencing in Arabidopsis. Proceedings of The National Academy of Sciences of The United States of America, 104 (37), 14741-14746. doi: 10.1073/pnas.0706701104
Fusaro, Adriana F., Matthew, Louisa, Smith, Neil A., Curtin, Shaun J., Dedic-Hagan, Jasmina, Ellacott, Geoff A., Watson, John M., Wang, Ming-Bo, Brosnan, Chris, Carroll, Bernard J. and Waterhouse, Peter M. (2006). RNA interference-inducing hairpin RNAs in plants act through the viral defence pathway. Embo Reports, 7 (11), 1168-1175. doi: 10.1038/sj.embor.7400837
Conference Papers
Brosnan, Christopher A. (2025). Mechanistic Dissection Exogenously applied RNAi-biopesticides. European COST Action meeting on exRNAs, Hamburg, Germany, 11-13 June 2025.
Brosnan, Christopher A. (2025). Mechanical dissection and functional assessment of exogenous RNAi by active small RNA sequencing. Australasian Plant Pathology Society conference, Sydney, NSW, Australia, 26-28 May 2025.
Brosnan, Christopher A. (2025). Assessment of dsRNA for the control of blackleg disease. National Canola Pathology Workshop, Melbourne, VIC, Australia, 5 March 2025.
Brosnan, Christopher A. (2024). Nanoparticle-mediated delivery of HLB targeting VIGS vectors. Australasian Plant Virology Workshop, Gold Coast, QLD, Australia, 29-31 October 2024.
Brosnan, Christopher A. (2024). Harnessing RNAi functionality and mobility for effective crop protection. International Plant Molecular Biology conference, Cairns, QLD, Australia, 24-28 June 2024.
Brosnan, Christopher A. (2023). Harnessing mobile, foliar applied double-stranded RNA for effective RNAi against plant pathogens. Australasian Plant Pathology Society conference, Adelaide, SA, Australia, 21 November 2023.
Brosnan, C. A., Mitter, N., Reyes, M., Constantin, M., Graham, M., Dietzgen, R.G. and Carroll, B. J. (2003). Tomato expression modulating sequences enhance double strand RNA-mediated resistance to potato virus Y in transgenic tobacco. 24th Annual Conference on the Organisation and Expression of the Genome, Lorne, Victoria, Australia, 16-20 February, 2003.
Ramage, C. M., Brosnan, C. A., Matthew, L., Reyes, M. and Carroll, B. J. (2002). Molecular genetic analysis of the two Defective embryo and meristems (Dem) genes in Arabidopsis. XIth International Association for Plant Tissue Culture and Biotechnology Congress, Orlando, USA, 23-28 June, 2002.
Brosnan, C. A., Matthew, L., Reyes, M., Ramage, C. and Carroll, B. J. (2002). Molecular genetic analysis of the two Defective embryo and meristems (DEM) genes in Arabidopsis. The Genome Conference, Lorne, 17-21 February, 2002.