Dr Karishma Mody
Amplify Fellow
Centre for Horticultural Science
+61 7 334 62318
Researcher biography
I am an agricultural biotechnologist specialising in applications of nanotechnology to improve animal health. My PhD was a part of a multi-disciplinary research project facilitated by the Queensland Government Research Partnerships at QAAFI. This research, for the first time, established silica nanomaterials as carriers and self-adjuvants for vaccine development and delivery against Bovine Viral Diarrhoea Virus. As a Research Fellow at QAAFI, I am leading the research using RNA interference technology and material science to develop sustainable solutions for real-world problems like sheep blowfly and sheep lice-infestation.
We are always seeking for motivated Honours and PhD applicants, please get in touch, if that sounds like you!
Journal Articles
Ong, Chian Teng, Mody, Karishma T., Cavallaro, Antonino S., Yan, Yakun, Nguyen, Loan T., Shao, Renfu, Mitter, Neena, Mahony, Timothy J. and Ross, Elizabeth M. (2024). Chromosome-Scale Genome Assembly of the Sheep-Biting Louse Bovicola ovis Using Nanopore Sequencing Data and Pore-C Analysis. International Journal of Molecular Sciences, 25 (14), 7824. doi: 10.3390/ijms25147824
Yang, Yunjia, Zhang, Bing, Yong, Jiaxi, James, Peter, Xu, Zhi Ping, Mitter, Neena, Mahony, Timothy J and Mody, Karishma T (2024). The use of cell and larval assays to identify target genes for RNA interference‐meditated control of the Australian sheep blowfly (Lucilia cuprina ). Pest Management Science. doi: 10.1002/ps.8190
Menezes, Pia S., Yan, Yakun, Yang, Yunjia, Mitter, Neena, Mahony, Timothy J. and Mody, Karishma T. (2022). RNAi-Based Biocontrol of Pests to Improve the Productivity and Welfare of Livestock Production. Applied Biosciences, 1 (3), 229-243. doi: 10.3390/applbiosci1030015
Lacasta, Anna, Mody, Karishma T, De Goeyse, Ine, Yu, Chengzhong, Zhang, Jun, Nyagwange, James, Mwalimu, Stephen, Awino, Elias, Saya, Rosemary, Njoroge, Thomas, Muriuki, Robert, Ndiwa, Nicholas, Poole, Elisabeth Jane, Zhang, Bing, Cavallaro, Antonino, Mahony, Timothy J, Steinaa, Lucilla, Mitter, Neena and Nene, Vishvanath (2021). Synergistic effect of two nanotechnologies enhances the protective capacity of the Theileria parva Sporozoite p67C antigen in cattle. Journal of Immunology, 206 (4), 686-699. doi: 10.4049/jimmunol.2000442
Mody, Karishma T., Zhang, Bing, Li, Xun, Fletcher, Nicholas L., Akhter, Dewan T., Jarrett, Sandy, Zhang, Jun, Yu, Chengzhong, Thurecht, Kristofer J., Mahony, Timothy J and Mitter, Neena (2021). Characterization of the biodistribution of a silica vesicle Nanovaccine carrying a Rhipicephalus (Boophilus) microplus protective antigen with in vivo live animal imaging. Frontiers in Bioengineering and Biotechnology, 8 606652, 1-11. doi: 10.3389/fbioe.2020.606652
Worrall, Elizabeth, Hamid, Aflaq, Mody, Karishma, Mitter, Neena and Pappu, Hanu (2018). Nanotechnology for plant disease management. Agronomy, 8 (12) 256, 285. doi: 10.3390/agronomy8120285
Zhang, Bing, Cavallaro, Antonio S., Mody, Karishma T., Zhang, Jun, Deringer, James R., Brown, Wendy C., Mahony, Timothy J., Yu, Chengzhong and Mitter, Neena (2016). Nanoparticle-based delivery of Anaplasma marginale membrane proteins, VirB9-1 and VirB10 produced in the Pichia pastoris expression system. Nanomaterials, 6 (11) 201, 201. doi: 10.3390/nano6110201
Mody, Karishma T., Mahony, Donna, Cavallaro, Antonino S., Zhang, Jun, Zhang, Bing, Mahony, Timothy J., Yu, Chengzhong and Mitter, Neena (2016). Correction: Silica Vesicle Nanovaccine Formulations Stimulate Long-Term Immune Responses to the Bovine Viral Diarrhoea Virus E2 Protein (vol 10, e0143507, 2015). Plos One, 11 (1) e0146631, 1-1. doi: 10.1371/journal.pone.0146631
Mody, Karishma T., Mahony, Donna, Cavallaro, Antonino S., Zhang, Jun, Zhang, Bing, Mahony, Timothy J., Yu, Chengzhong and Mitter, Neena (2015). Silica vesicle nanovaccine formulations stimulate long-term immune responses to the bovine viral diarrhoea virus e2 protein. PLoS One, 10 (12) e0143507, 1-16. doi: 10.1371/journal.pone.0143507
Mahony, Donna, Mody, Karishma T., Cavallaro, Antonino S., Hu, Qiuhong, Mahony, Timothy J., Qiao, Shizhang and Mitter, Neena (2015). Immunisation of Sheep with Bovine Viral Diarrhoea Virus, E2 Protein Using a Freeze-Dried Hollow Silica Mesoporous Nanoparticle Formulation. Plos One, 10 (11) e0141870, e0141870. doi: 10.1371/journal.pone.0141870
Mody, Karishma T., Mahony, Donna, Zhang, Jun, Cavallaro, Antonino S., Zhang, Bing, Popat, Amirali, Mahony, Timothy J., Yu, Chengzhong and Mitter, Neena (2014). Silica vesicles as nanocarriers and adjuvants for generating both antibody and T-cell mediated immune resposes to Bovine Viral Diarrhoea Virus E2 protein. Biomaterials, 35 (37), 9972-9983. doi: 10.1016/j.biomaterials.2014.08.044
Mody, Karishma T., Mahony, Donna, Cavallaro, Antonino S., Stahr, Frances, Qiao, Shi Zhang, Mahony, Timothy J. and Mitter, Neena (2014). Freeze-drying of ovalbumin loaded mesoporous silica nanoparticle vaccine formulation increases antigen stability under ambient conditions. International Journal of Pharmaceutics, 465 (1-2), 325-332. doi: 10.1016/j.ijpharm.2014.01.037
Mahony, D., Cavallaro, A. S., Mody, K. T., Xiong, L., Mahony, T. J., Qiao, S. Z. and Mitter, Neena (2014). In vivo delivery of bovine viral diahorrea virus, E2 protein using hollow mesoporous silica nanoparticles. Nanoscale, 6 (12), 6617-6626. doi: 10.1039/C4NR01202J
Mody, Karishma T., Popat, Amirali, Mahony, Donna, Cavallaro, Antonino S., Yu, Chengzhong and Mitter, Neena (2013). Mesoporous silica nanoparticles as antigen carriers and adjuvants for vaccine delivery. Nanoscale, 5 (12), 5167-5179. doi: 10.1039/c3nr00357d
Mody, Karishma, Mahony, Donna, Mahony, Tim and Mitter, Neena (2012). Freeze-drying of protein-loaded nanoparticles for vaccine delivery. Drug Delivery Letters, 2 (2), 83-91. doi: 10.2174/2210304x11202020083
Conference Paper
Mody, Karishma T., Zhang, Bing, Li, Xun, Jain, Ritesh, Li, Peng, James, Peter, Mahony, Timothy J., Xu, Zhiping and Mitter, Neena (2020). Topical RNAi for Sustainable Animal Health. TropAg 2019, Brisbane, QLD Australia, 11-13 November 2019. Basel, Switzerland: MDPI. doi: 10.3390/proceedings2019036170
Thesis
Mody, Karishma (2015). Development of nanoparticle based vaccine delivery systems. PhD Thesis, Queensland Alliance for Agriculture and Food Innovation, The University of Queensland. doi: 10.14264/uql.2015.934