Professor Timothy Mahony

Acting Centre Director, Centre for Animal Science

Queensland Alliance for Agriculture and Food Innovation

t.mahony@uq.edu.au

Researcher biography

Prof Tim Mahony joined QAAFI's Centre for Animal Science in October 2010, after 15 years of conducting research projects with the Queensland Government. He obtained his PhD from James Cook University in the area of molecular microbiology. During 2001 and 2002, Prof Mahony was a visiting professor at the University of Saskatchewan.

Research interests

Dr Mahony's research interests are in the area of molecular virology revolving around improving viral disease control in production animals such as cattle and poultry. His group is characterising the molecular interactions between invading pathogens and the subsequent host responses with the goal of developing new vaccines and diagnostic technologies. A key component of this work includes improving the basic understanding of the molecular mechanisms that underpin and drive viral virulence and evolution. Next-generation sequencing has been used to sequence the genomes of herpesviruses and adenoviruses from a variety of species including, cattle, chickens, marsupials, horses, and crocodiles. Prof Mahony's team is also investigating the role of virally encoded microRNAs in virulence, replication, and disease development. His group was one of the first in the world to apply bacterial artificial chromosome infectious clone technology for the efficient manipulation of herpesviruses that have large DNA genomes. These strategies are also being exploited to understand viral gene function and the development of vaccines.

Currently, Prof Mahony is researching risk factors that protect and predispose feedlot cattle to developing bovine respiratory disease (BRD). He is also leading the development of new vaccines for BRD and cattle tick infestations. Prof Mahony has also led the development of new vaccine delivery technologies for the poultry industry targeting the application of in ovo strategies. Prof Mahony research into improving animal health is increasing industry productivity, food safety, and consumer confidence in food products and he is keen to explore collaborations with other scientists in this area.

Prof Mahony has a strong interest to work with post-graduate students and has supervised a number of post-graduate students from Australia and overseas. These projects have covered research areas in molecular virology, animal health, vaccine development, and pathogen-host interactions.

Publications

Book Chapters (4)

Journal Articles (99)

Conference Papers (9)

Department Technical Report (1)

Book Chapters

Robinson, K. E. and Mahony, T. J. (2020). The construction and evaluation of herpesvirus vectors. Viral vectors in veterinary vaccine development. (pp. 95-110) Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-030-51927-8_7

Mahony, Timothy John (2016). Betaherpesvirinae (Suid Herpesvirus 2). Molecular detection of animal viral pathogens. (pp. 747-752) edited by Dongyou Liu. Boca Raton, FL, United States: CRC Press. doi: 10.1201/b19719-1

Robinson, Karl E. and Mahony, Timothy J. (2015). Herpesvirus mutagenesis facilitated by infectious bacterial artiﬁcial chromosomes (iBACs). Bacterial artiﬁcial chromosomes. (pp. 181-197) edited by Kumaran Narayanan. New York, NY, United States: Springer Science+Business Media. doi: 10.1007/978-1-4939-1652-8_8

Mahony, Timothy J., McCarthy, Fiona M., Gravel, Jennifer L. and Young, Peter L. (2005). Construction of a gene inactivation library for Bovine herpesvirus 1 using infectious clone technology. DNA viruses: Methods and protocols. (pp. 387-400) edited by Paul M. Lieberman. Totowa, NJ, United States: Humana Press. doi: 10.1385/1-59259-848-X:387

Journal Articles

Suksai, Sucharat, Attasart, Pongsopee, Angsujinda, Kitipong, Zhang, Bing, Xu, Zhi Ping, Mitter, Neena, Mahony, Timothy J. and Assavalapsakul, Wanchai (2025). Delivery of virus-specific dsRNA using a composite nanomaterial improves the protection of shrimp (Litopenaeus vannamei) against yellow head virus challenge. Aquaculture, 595 741570, 741570. doi: 10.1016/j.aquaculture.2024.741570

Hayes, Ben J., Mahony, Timothy J., Villiers, Kira, Warburton, Christie, Kemper, Kathryn E., Dinglasan, Eric, Robinson, Hannah, Powell, Owen, Voss-Fels, Kai, Godwin, Ian D. and Hickey, Lee T. (2024). Potential approaches to create ultimate genotypes in crops and livestock. Nature Genetics, 56 (11), 2310-2317. doi: 10.1038/s41588-024-01942-0

Ong, Chian Teng, Mody, Karishma T., Cavallaro, Antonino S., Yan, Yakun, Nguyen, Loan T., Shao, Renfu, Mitter, Neena, Mahony, Timothy J. and Ross, Elizabeth M. (2024). Chromosome-Scale Genome Assembly of the Sheep-Biting Louse Bovicola ovis Using Nanopore Sequencing Data and Pore-C Analysis. International Journal of Molecular Sciences, 25 (14) 7824, 7824. doi: 10.3390/ijms25147824

Yang, Yunjia, Zhang, Bing, Yong, Jiaxi, James, Peter, Xu, Zhi Ping, Mitter, Neena, Mahony, Timothy J and Mody, Karishma T (2024). The use of cell and larval assays to identify target genes for RNA interference‐meditated control of the Australian sheep blowfly (Lucilia cuprina). Pest Management Science, 80 (9), 4686-4698. doi: 10.1002/ps.8190

Owada, Kei, Mahony, Timothy J., Ambrose, Rebecca K., Hayes, Ben J. and Soares Magalhães, Ricardo J. (2024). Epidemiological Risk Factors and Modelling Approaches for Risk Assessment of Lumpy Skin Disease Virus Introduction and Spread: Methodological Review and Implications for Risk-Based Surveillance in Australia. Transboundary and Emerging Diseases, 2024 ARTN 3090226, 1-16. doi: 10.1155/2024/3090226

Hayes, B J, Duff, C J, Hine, B C and Mahony, T J (2024). Short Communication: Genomic estimated breeding values for bovine respiratory disease resistance in Angus feedlot cattle. Journal of Animal Science, 102 skae113. doi: 10.1093/jas/skae113

Babington, Sarah, Tilbrook, Alan J., Maloney, Shane K., Fernandes, Jill N., Crowley, Tamsyn M., Ding, Luoyang, Fox, Archa H., Zhang, Song, Kho, Elise A., Cozzolino, Daniel, Mahony, Timothy J. and Blache, Dominique (2024). Finding biomarkers of experience in animals. Journal of Animal Science and Biotechnology, 15 (1) 28, 1-20. doi: 10.1186/s40104-023-00989-z

Mahony, Timothy J., Briody, Tatiana E. and Ommeh, Sheila C. (2024). Can the Revolution in mRNA-Based Vaccine Technologies Solve the Intractable Health Issues of Current Ruminant Production Systems?. Vaccines, 12 (2) 152, 152. doi: 10.3390/vaccines12020152

Angsujinda, Kitipong, Peala, Wisuttiya, Sittidech, Akekarach, Wanganurakkul, Saruda, Mahony, Timothy J., Wang, Sheng-Fan, Smith, Duncan R., Chintapitaksakul, Lerdchai, Khongchareonporn, Nanthika and Assavalapsakul, Wanchai (2024). Development of a lateral flow assay for rapid and accurate detection of chicken anemia virus. Poultry Science, 103 (3) 103432, 103432. doi: 10.1016/j.psj.2024.103432

Alexander, A. L., Doyle, E. K., Ingham, A. B., Colditz, I. G., Andronicos, N. M., Hine, B. C. and Mahony, T. J. (2024). Does the immune stimulant Amplimune® modulate humoral and cytokine responses to commercial bovine respiratory disease vaccines in cattle?. Animal Production Science, 64 (4) AN23235. doi: 10.1071/an23235

Lamb, H. J., Nguyen, L. T., Briody, T. E., Ambrose, R. K., Hayes, B. J., Mahony, T. J. and Ross, E. M. (2023). Skim-Nanopore sequencing for routine genomic evaluation and bacterial pathogen detection in cattle. Animal Production Science, 63 (11), 1074-1085. doi: 10.1071/an22451

Speck, Peter, Mackenzie, Jason, Bull, Rowena A., Slobedman, Barry, Drummer, Heidi, Fraser, Johanna, Herrero, Lara, Helbig, Karla, Londrigan, Sarah, Moseley, Gregory, Prow, Natalie, Hansman, Grant, Edwards, Robert, Ahlenstiel, Chantelle, Abendroth, Allison, Tscharke, David, Hobson-Peters, Jody, Kriiger-Loterio, Robson, Parry, Rhys, Marsh, Glenn, Harding, Emma, Jacques, David A., Gartner, Matthew J., Lee, Wen Shi, McAuley, Julie, Vaz, Paola, Sainsbury, Frank, Tate, Michelle D., Sinclair, Jane ... Young, Paul (2023). Statement in Support of: “Virology under the Microscope—a Call for Rational Discourse”. Journal of Virology, 97 (5), e0045123. doi: 10.1128/jvi.00451-23

Ambrose, Rebecca K., Blakebrough-Hall, Claudia, Gravel, Jennifer L., Gonzalez, Luciano A. and Mahony, Timothy J. (2023). Characterisation of the upper respiratory tract virome of feedlot cattle and its association with bovine respiratory disease. Viruses, 15 (2) 455. doi: 10.3390/v15020455

Menezes, Pia S., Yan, Yakun, Yang, Yunjia, Mitter, Neena, Mahony, Timothy J. and Mody, Karishma T. (2022). RNAi-Based Biocontrol of Pests to Improve the Productivity and Welfare of Livestock Production. Applied Biosciences, 1 (3), 229-243. doi: 10.3390/applbiosci1030015

Salgadu, Ayesha, Cheung, Allison, Schibrowski, Meghan L., Wawegama, Nadeeka K., Mahony, Timothy J., Stevenson, Mark A., Browning, Glenn F., Barnes, Tamsin S. and Firestone, Simon M. (2022). Bayesian latent class analysis to estimate the optimal cut-off for the MilA ELISA for the detection of Mycoplasma bovis antibodies in sera, accounting for repeated measures. Preventive Veterinary Medicine, 205 105694, 1-8. doi: 10.1016/j.prevetmed.2022.105694

Blakebrough-Hall, Claudia, Hick, Paul, Mahony, T. J. and González, Luciano A. (2022). Factors associated with bovine respiratory disease case fatality in feedlot cattle. Journal of Animal Science, 100 (1) skab361. doi: 10.1093/jas/skab361

Pumtang-On, Pongthorn, Mahony, Timothy J., Hill, Rodney A., Pavic, Anthony and Vanniasinkam, Thiru (2021). Investigation of Campylobacter colonization in three Australian commercial free-range broiler farms. Poultry Science, 100 (3) 100891, 1-12. doi: 10.1016/j.psj.2020.12.004

Lacasta, Anna, Mody, Karishma T, De Goeyse, Ine, Yu, Chengzhong, Zhang, Jun, Nyagwange, James, Mwalimu, Stephen, Awino, Elias, Saya, Rosemary, Njoroge, Thomas, Muriuki, Robert, Ndiwa, Nicholas, Poole, Elisabeth Jane, Zhang, Bing, Cavallaro, Antonino, Mahony, Timothy J, Steinaa, Lucilla, Mitter, Neena and Nene, Vishvanath (2021). Synergistic effect of two nanotechnologies enhances the protective capacity of the Theileria parva Sporozoite p67C antigen in cattle. Journal of Immunology, 206 (4), 686-699. doi: 10.4049/jimmunol.2000442

Pumtang-on, Pongthorn, Mahony, Timothy J., Hill, Rodney A. and Vanniasinkam, Thiru (2021). A systematic review of Campylobacter jejuni vaccine candidates for chickens. Microorganisms, 9 (2) 397, 1-48. doi: 10.3390/microorganisms9020397

Mody, Karishma T., Zhang, Bing, Li, Xun, Fletcher, Nicholas L., Akhter, Dewan T., Jarrett, Sandy, Zhang, Jun, Yu, Chengzhong, Thurecht, Kristofer J., Mahony, Timothy J and Mitter, Neena (2021). Characterization of the biodistribution of a silica vesicle Nanovaccine carrying a Rhipicephalus (Boophilus) microplus protective antigen with in vivo live animal imaging. Frontiers in Bioengineering and Biotechnology, 8 606652, 1-11. doi: 10.3389/fbioe.2020.606652

Vaz, P. K., Mahony, T. J., Hartley, C. A., Motha, J. and Devlin, J. M. (2021). Genome sequences of two marsupial simplex viruses, macropodid alphaherpesviruses 2 and 4. Microbiology Resource Announcements, 10 (2) e01189-20. doi: 10.1128/mra.01189-20

Angsujinda, Kitipong, Mahony, Timothy J., Smith, Duncan R., Kettratad, Jes and Assavalapsakul, Wanchai (2020). Expression profile of selected genes of the E-11 cell line in response to red-spotted grouper nervous necrosis virus infection. Aquaculture Reports, 18 100468, 100468. doi: 10.1016/j.aqrep.2020.100468

Devi, Aruna, Mahony, Timothy J., Wilkinson, Jenny M. and Vanniasinkam, Thiru (2019). Antimicrobial susceptibility of clinical isolates of Campylobacter jejuni from New South Wales, Australia. Journal of Global Antimicrobial Resistance, 16, 76-80. doi: 10.1016/j.jgar.2018.09.011

Chen, Weiyu, Zuo, Huali, Rolfe, Barbara, Schembri, Mark A., Cobbold, Rowland N., Zhang, Bing, Mahony, Timothy J. and Xu, Zhi Ping (2018). Clay nanoparticles co-deliver three antigens to promote potent immune responses against pathogenic Escherichia coli. Journal of Controlled Release, 292, 196-209. doi: 10.1016/j.jconrel.2018.11.008

Kanokudom, Sitthichai, Mahony, Timothy J., Smith, Duncan R. and Assavalapsakul, Wanchai (2018). Modulation of bovine herpesvirus 1 infection by virally encoded microRNAs. Virus Research, 257, 1-6. doi: 10.1016/j.virusres.2018.08.022

Schibrowski, M. L., Gibson, J. S., Hay, K. E., Mahony, T. J. and Barnes, T. S. (2018). Mycoplasma bovis and bovine respiratory disease: a risk factor study in Australian feeder cattle. Preventive Veterinary Medicine, 157, 152-161. doi: 10.1016/j.prevetmed.2018.06.005

Chen, Weiyu, Zuo, Huali, Li, Bei, Duan, Chengcheng, Rolfe, Barbara, Zhang, Bing, Mahony, Timothy J and Xu, Zhi Ping (2018). Clay nanoparticles elicit long-term immune responses by forming biodegradable depots for sustained antigen stimulation. Small, 14 (19) 1704465, e1704465. doi: 10.1002/smll.201704465

Schibrowski, Meghan L., Barnes, Tamsin S., Wawegama, Nadeeka K., Vance, Megan E., Markham, Philip F., Mansell, Peter D., Marenda, Marc S., Kanci, Anna, Perez-Casal, José, Browning, Glenn F., Gibson, Justine S. and Mahony, Timothy J. (2018). The performance of three immune assays to assess the serological status of cattle experimentally exposed to mycoplasma bovis. Veterinary Sciences , 5 (1) 27, 27. doi: 10.3390/vetsci5010027

Ambrose, Rebecca K, Gravel, Jennifer L, Commins, Margaret A, Fowler, Elizabeth V and Mahony, Timothy J (2018). In Vivo Characterisation of Five Strains of Bovine Viral Diarrhoea Virus 1 (Subgenotype 1c). Pathogens (Basel, Switzerland), 7 (1) 12, 1-18. doi: 10.3390/pathogens7010012

Chen, Weiyu, Zuo, Huali, Mahony, Timothy J, Zhang, Bing, Rolfe, Barbara and Xu, Zhi Ping (2017). Efficient induction of comprehensive immune responses to control pathogenic E. coli by clay nano-adjuvant with the moderate size and surface charge. Scientific reports, 7 (1) 13367, 1-12. doi: 10.1038/s41598-017-13570-2

Hay, K. E., Morton, J. M., Clements, A. C. A., Mahony, T. J. and Barnes, T. S. (2017). Population-level effects of risk factors for bovine respiratory disease in Australian feedlot cattle. Preventive Veterinary Medicine, 140, 78-86. doi: 10.1016/j.prevetmed.2017.03.001

Zhang, Bing, Cavallaro, Antonio S., Mody, Karishma T., Zhang, Jun, Deringer, James R., Brown, Wendy C., Mahony, Timothy J., Yu, Chengzhong and Mitter, Neena (2016). Nanoparticle-based delivery of Anaplasma marginale membrane proteins, VirB9-1 and VirB10 produced in the Pichia pastoris expression system. Nanomaterials, 6 (11) 201, 201. doi: 10.3390/nano6110201

Besier, A. S., Mahony, T. J., Crockford, M., Gravel, J. L., Chapman, T. F. and O'Dea, M. A. (2016). Alphaherpesvirus-associated disease in greater bilbies (Macrotis lagotis). Australian Veterinary Journal, 94 (6), 208-212. doi: 10.1111/avj.12447

Hay, K. E., Morton, J. M., Clements, A. C. A., Mahony, T. J. and Barnes, T. S. (2016). Associations between feedlot management practices and bovine respiratory disease in Australian feedlot cattle. Preventive Veterinary Medicine, 128, 23-32. doi: 10.1016/j.prevetmed.2016.03.017

Hay, K. E., Barnes, T. S., Morton, J. M., Gravel, J. L., Commins, M. A., Horwood, P. F., Ambrose, R. C., Clements, A. C. A. and Mahony, T. J. (2016). Associations between exposure to viruses and bovine respiratory disease in Australian feedlot cattle. Preventive Veterinary Medicine, 127, 121-133. doi: 10.1016/j.prevetmed.2016.01.024

Hay, K. E., Morton, J. M., Schibrowski, M. L., Clements, A. C. A., Mahony, T. J. and Barnes, T. S. (2016). Associations between prior management of cattle and risk of bovine respiratory disease in feedlot cattle. Preventive Veterinary Medicine, 127, 37-43. doi: 10.1016/j.prevetmed.2016.02.006

Wawegama, Nadeeka K., Markham, Philip F., Kanci, Anna, Schibrowski, Meghan, Oswin, Sally, Barnes, Tamsin S., Firestone, Simon M., Mahony, Timothy J. and Browning, Glenn F. (2016). Evaluation of an IgG enzyme-linked immunosorbent assay as a serological assay for detection of mycoplasma bovis infection in feedlot cattle. Journal of Clinical Microbiology, 54 (5), 1269-1275. doi: 10.1128/JCM.02492-15

Mahony, Timothy J. (2016). Untangling the complexity of diseases such as calf diarrhoea is crucial to future productivity. Veterinary Journal, 210, 3-4. doi: 10.1016/j.tvjl.2015.11.005

Chen, Weiyu, Zhang, Bing, Mahony, Timothy, Gu, Wenyi, Rolfe, Barbara and Xu, Zhi Ping (2016). Efficient and durable vaccine against Intimin β of Diarrheagenic E. Coli induced by clay nanoparticles. Small, 12 (12), 1627-1639. doi: 10.1002/smll.201503359

Hay, K. E., Morton, J. M., Mahony, T. J., Clements, A. C. A. and Barnes, T. S. (2016). Associations between animal characteristic and environmental risk factors and bovine respiratory disease in Australian feedlot cattle. Preventive Veterinary Medicine, 125, 66-74. doi: 10.1016/j.prevetmed.2016.01.013

Hay, K. E., Ambrose, R. C. K., Morton, J. M., Horwood, P. F., Gravel, J. L., Waldron, S., Commins, M. A., Fowler, E. V., Clements, A. C. A., Barnes, T. S. and Mahony, T. J. (2016). Effects of exposure to Bovine viral diarrhoea virus 1 on risk of bovine respiratory disease in Australian feedlot cattle. Preventive Veterinary Medicine, 126, 159-169. doi: 10.1016/j.prevetmed.2016.01.025

Vaz, Paola K., Mahony, Timothy J., Hartley, Carol A., Fowler, Elizabeth V., Ficorilli, Nino, Lee, Sang W., Gilkerson, James R., Browning, Glenn F. and Devlin, Joanne M. (2016). The first genome sequence of a metatherian herpesvirus: Macropodid herpesvirus 1. BMC Genomics, 17 (1) 70, 70. doi: 10.1186/s12864-016-2390-2

Mody, Karishma T., Mahony, Donna, Cavallaro, Antonino S., Zhang, Jun, Zhang, Bing, Mahony, Timothy J., Yu, Chengzhong and Mitter, Neena (2016). Correction: Silica Vesicle Nanovaccine Formulations Stimulate Long-Term Immune Responses to the Bovine Viral Diarrhoea Virus E2 Protein (vol 10, e0143507, 2015). Plos One, 11 (1) e0146631, 1-1. doi: 10.1371/journal.pone.0146631

Devi, Aruna, Gunjilac, Adam S., Wilkinson, Jenny M., Vanniasinkam, Thiru and Mahony, Timothy J. (2016). Prevalence of Campylobacter spp. in diarrhoea samples from patients in New South Wales, Australia. International Microbiology, 19 (1), 33-37. doi: 10.2436/20.1501.01.261

Mody, Karishma T., Mahony, Donna, Cavallaro, Antonino S., Zhang, Jun, Zhang, Bing, Mahony, Timothy J., Yu, Chengzhong and Mitter, Neena (2015). Silica vesicle nanovaccine formulations stimulate long-term immune responses to the bovine viral diarrhoea virus e2 protein. PLoS One, 10 (12) e0143507, 1-16. doi: 10.1371/journal.pone.0143507

Mahony, Donna, Mody, Karishma T., Cavallaro, Antonino S., Hu, Qiuhong, Mahony, Timothy J., Qiao, Shizhang and Mitter, Neena (2015). Immunisation of Sheep with Bovine Viral Diarrhoea Virus, E2 Protein Using a Freeze-Dried Hollow Silica Mesoporous Nanoparticle Formulation. Plos One, 10 (11) e0141870, e0141870. doi: 10.1371/journal.pone.0141870

Giles, Carla, Vanniasinkam, Thiru, Barton, Mary and Mahony, Timothy J. (2015). Characterisation of the Equine adenovirus 2 genome. Veterinary Microbiology, 179 (3-4), 184-189. doi: 10.1016/j.vetmic.2015.07.024

Mahony, T. J. (2015). Understanding the molecular basis of disease is crucial to improving the design and construction of herpesviral vectors for veterinary vaccines. Vaccine, 33 (44), 5897-5904. doi: 10.1016/j.vaccine.2015.09.028

Hall, Robyn N., Meers, Joanne, Fowler, Elizabeth V. and Mahony, Timothy J. (2015). Identification of non-essential loci within the Meleagrid herpesvirus 1 genome. Virology Journal, 12 (1) 130, 130.1-130.12. doi: 10.1186/s12985-015-0362-9

Mahony, Timothy J., Hall, Robyn N., Walkden-Brown, Stephen, Meers, Joanne, Gravel, Jennifer L., West, Lani, Hardy, Vanessa, Islam, A. F. M. Fakhrul, Fowler, Elizabeth V. and Mitter, Neena (2015). Genomic deletions and mutations resulting in the loss of eight genes reduce the in vivo replication capacity of Meleagrid herpesvirus 1. Virus Genes, 51 (1), 85-95. doi: 10.1007/s11262-015-1216-7

Goldspink, L. K., Mollinger, J. L., Barnes, T. S., Groves, M., Mahony, T. J. and Gibson, J. S. (2015). Antimicrobial susceptibility of Histophilus somni isolated from clinically affected cattle in Australia. Veterinary Journal, 203 (2), 239-243. doi: 10.1016/j.tvjl.2014.12.008

Devi, Aruna, Wilkinson, Jenny, Mahony, Timothy and Vanniasinkam, Thiru (2014). Detection of Campylobacter in human faecal samples in Fiji. Western Pacific Surveillance and Response Journal, 5 (4), 30-33. doi: 10.5365/WPSAR.2014.5.2.007

Mody, Karishma T., Mahony, Donna, Zhang, Jun, Cavallaro, Antonino S., Zhang, Bing, Popat, Amirali, Mahony, Timothy J., Yu, Chengzhong and Mitter, Neena (2014). Silica vesicles as nanocarriers and adjuvants for generating both antibody and T-cell mediated immune resposes to Bovine Viral Diarrhoea Virus E2 protein. Biomaterials, 35 (37), 9972-9983. doi: 10.1016/j.biomaterials.2014.08.044

Hay, K. E., Barnes, T. S., Morton, J. M., Clements, A. C. A. and Mahony, T. J. (2014). Risk factors for bovine respiratory disease in Australian feedlot cattle: use of a causal diagram-informed approach to estimate effects of animal mixing and movements before feedlot entry. Preventive Veterinary Medicine, 117 (1), 160-169. doi: 10.1016/j.prevetmed.2014.07.001

Easton, Donna M., Allsopp, Luke P., Phan, Minh-Duy, Gomes Moriel, Danilo, Goh, Guan Kai, Beatson, Scott A., Mahony, Timothy J., Cobbold, Rowland N. and Schembri, Mark A. (2014). The intimin-like protein FdeC is regulated by H-NS and temperature in Enterohaemorrhagic Escherichia coli. Applied and Environmental Microbiology, 80 (23), 7337-7347. doi: 10.1128/AEM.02114-14

Mody, Karishma T., Mahony, Donna, Cavallaro, Antonino S., Stahr, Frances, Qiao, Shi Zhang, Mahony, Timothy J. and Mitter, Neena (2014). Freeze-drying of ovalbumin loaded mesoporous silica nanoparticle vaccine formulation increases antigen stability under ambient conditions. International Journal of Pharmaceutics, 465 (1-2), 325-332. doi: 10.1016/j.ijpharm.2014.01.037

Mahony, D., Cavallaro, A. S., Mody, K. T., Xiong, L., Mahony, T. J., Qiao, S. Z. and Mitter, Neena (2014). In vivo delivery of bovine viral diahorrea virus, E2 protein using hollow mesoporous silica nanoparticles. Nanoscale, 6 (12), 6617-6626. doi: 10.1039/C4NR01202J

Horwood, P. F., Schibrowski, M. L., Fowler, E. V., Gibson, J. S., Barnes, T. S. and Mahony, T. J. (2014). Is Mycoplasma bovis a missing component of the bovine respiratory disease complex in Australia?. Australian Veterinary Journal, 92 (6), 185-191. doi: 10.1111/avj.12184

Mahony, Timothy J. (2014). Biosecurity strategies for the beef industry. Australasian Biotechnology, 24 (3), 60-60.

Mahony, Donna, Cavallaro, Antonino S., Stahr, Frances, Mahony, Timothy J., Qiao, Shi Zhang and Mitter, Neena (2013). Mesoporous silica nanoparticles act as a self-adjuvant for ovalbumin model antigen in mice. Small, 9 (18), 3138-3146. doi: 10.1002/smll.201300012

Hall, Robyn N., Meers, Joanne, Mitter, Neena, Fowler, Elizabeth V. and Mahony, Timothy J. (2013). The meleagrid herpesvirus 1 genome is partially resistant to transposition. Avian Diseases, 57 (2 SUPPL. 1), 380-386. doi: 10.1637/10339-082912-Reg.1

Pacioni, Carlo, Johansen, Cheryl A., Mahony, Timothy J., O'Dea, Mark A., Robertson, Ian D., Wayne, Adrian F. and Ellis, Trevor (2013). A virological investigation into declining woylie populations. Australian Journal of Zoology, 61 (6), 446-453. doi: 10.1071/ZO13077

Hartawan, Risza, Dharmayanti, Ni Luh Putu Indi, Robinson, Karl, Mahony, Timothy and Meers, Joanne (2012). Expression of Two N1 Clones with Single Amino Acid Dissimilarity of Avian Influenza H5N1 Virus. HAYATI Journal of Biosciences, 19 (4), 169-176. doi: 10.4308/hjb.19.4.169

Mody, Karishma, Mahony, Donna, Mahony, Tim and Mitter, Neena (2012). Freeze-drying of protein-loaded nanoparticles for vaccine delivery. Drug Delivery Letters, 2 (2), 83-91. doi: 10.2174/2210304x11202020083

Hall, Robyn N., Meers, Joanne, Fowler, Elizabeth and Mahony, Timothy (2012). Back to BAC: The use of infectious clone technologies for viral mutagenesis. Viruses, 4 (2), 211-235. doi: 10.3390/v4020211

Cavanagh, Heather M. A., Mahony, Timothy J. and Vanniasinkam, Thiru (2012). Genetic characterization of equine adenovirus type 1. Veterinary Microbiology, 155 (1), 33-37. doi: 10.1016/j.vetmic.2011.08.014

Cavallaro, Antonio S., Mahony, Donna, Commins, Margaret, Mahony, Timothy J. and Mitter, Neena (2011). Endotoxin-free purification for the isolation of Bovine Viral Diarrhoea Virus E2 protein from insoluble inclusion body aggregates. Microbial Cell Factories, 10 (1) 57, 57.1-57.9. doi: 10.1186/1475-2859-10-57

Hartawan, Risza, Robinson, K., Mahony, T. and Meers, J. (2011). In vitro expression of native H5 and N1 genes of avian influenza virus by using Green Fluorescent Protein as reporter. Indonesian Journal of Animal and Veterinary Sciences, 16 (3), 234-241. doi: 10.14334/jitv.v16i3.618

Easton, Donna M., Totsika, Makrina, Allsopp, Luke P., Phan, Minh-Duy, Idris, Adi, Wurpel, Daniël J., Sherlock, Orla, Zhang, Bing, Venturini, Carola, Beatson, Scott A., Mahony, Timothy J., Cobbold, Rowland N. and Schembri, Mark A. (2011). Characterization of EhaJ, a new autotransporter protein from enterohemorrhagic and enteropathogenic Escherichia coli. Frontiers in Microbiology: Frontiers in Cellular and Infection Microbiology, 2 (JUNE), 120.1-120.9. doi: 10.3389/fmicb.2011.00120

Horwood, Paul Francis and Mahony, Timothy John (2011). Multiplex real-time RT-PCR detection of three viruses associated with the bovine respiratory disease complex. Journal of Virological Methods, 171 (2), 360-363. doi: 10.1016/j.jviromet.2010.11.020

Robinson, K. E., Meers, J. and Mahony, T. J. (2010). Polyvalent Alphaherpesvirus vectors in veterinary vaccine research. Current Topics in Virology, 8, 71-88.

Mahony, Timothy J. (2010). Bovine herpesvirus: What is missing from our understanding of the relationship between BoHV-1 and BoHV-5?. Veterinary Journal, 184 (2), 124-125. doi: 10.1016/j.tvjl.2009.06.020

Hartawan, Risza, Robinson, Karl, Mahony, Timothy and Meers, Joanne (2010). Characterisation of the H5 and N1 genes of an Indonesian highly pathogenic avian influenza virus isolate by sequencing of multiple clone approach. Indonesian Journal of Animal and Veterinary Sciences, 15 (3), 240-251. doi: 10.14334/jitv.v15i3.663

Glazov, Evgeny A., Horwood, Paul F., Assavalapsakul, Wanchai, Kongsuwan, Kritaya, Mitchell, Roger W., Mitter, Neena and Mahony, Timothy J. (2010). Characterization of microRNAs encoded by the bovine herpesvirus 1 genome. Journal of General Virology, 91 (1), 32-41. doi: 10.1099/vir.0.014290-0

Moody, N. J. G., Horwood, P. F., Reynolds, A., Mahony, T. J., Anderson, I. G. and Oakey, H. J. (2009). Molecular detection and phylogenetic analysis of betanodavirus isolates from Australian finfish. Diseases of Aquatic Organisms, 87 (3), 151-160. doi: 10.3354/dao02130

Elkington, R. A., Humphries, M., Commins, M., Maugeri, N., Tierney, T. and Mahony, T. J. (2009). A Lucilia cuprina excretory-secretory protein inhibits the early phase of lymphocyte activation and subsequent proliferation. Parasite Immunology, 31 (12), 750-765. doi: 10.1111/j.1365-3024.2009.01154.x

Glazov, Evgeny A., Kongsuwan, Kritaya, Assavalapsakul, Wanchai, Horwood, Paul F., Mitter, Neena and Mahony, Timothy J. (2009). Repertoire of bovine miRNA and miRNA-like small regulatory RNAs expressed upon viral infection. PLoS One, 4 (7) e6349, e6349-1-e6349-6. doi: 10.1371/journal.pone.0006349

McCarthy, Fiona M., Mahony, Timothy J., Mark S. Parcells and Shane C. Burgess (2009). Understanding animal viruses using the Gene Ontology. Trends in Microbiology, 17 (7), 328-335. doi: 10.1016/j.tim.2009.04.006

Robinson, Karl E., Meers, Joanne, Gravel, Jennifer L., McCarthy, Fiona M. and Mahony, Timothy J. (2008). The essential and non-essential genes of Bovine herpesvirus 1. Journal of General Virology, 89 (11), 2851-2863. doi: 10.1099/vir.0.2008/002501-0

Horwood, Paul Francis, Gravel, Jennifer Lillian and Mahony, Timothy John (2008). Identification of two distinct bovine parainfluenza virus type 3 genotypes. Journal of General Virology, 89 (7), 1643-1648. doi: 10.1099/vir.0.2008/000026-0

Elkington, Rebecca A. and Mahony, Timothy J. (2007). A blowfly strike vaccine requires an understanding of host-pathogen interactions. Vaccine, 25 (28), 5133-5145. doi: 10.1016/j.vaccine.2007.04.074

Islam, Aminul, Cheetham, Brian F., Mahony, Timothy J., Young, Peter L. and Walkden-Brown, Stephen W. (2006). Absolute quantitation of Marek's disease virus and Herpesvirus of turkeys in chicken lymphocyte, feather tip and dust samples using real-time PCR. Journal of Virological Methods, 132 (1-2), 127-134. doi: 10.1016/j.jviromet.2005.10.009

Mahony, Timothy J., McCarthy, Fiona M., Gravel, Jennifer L., Corney, Bruce, Young, Peter L. and Vilcek, Stefan (2005). Genetic analysis of bovine viral diarrhoea viruses from Australia. Veterinary Microbiology, 106 (1-2), 1-6. doi: 10.1016/j.vetmic.2004.10.024

Mahony, Timothy J, McCarthy, Fiona M, Gravel, Jennifer L and Young, Peter L (2005). Construction of a gene inactivation library for Bovine herpesvirus 1 using infectious clone technology. Methods in molecular biology (Clifton, N.J.), 292, 387-400.

Islam, Aminul, Harrison, Bruce, Cheetham, Brian F., Mahony, Timothy J., Young, Peter L. and Walkden-Brown, Stephen W. (2004). Differential amplification and quantification of Marek’s Disease viruses using real-time polymerase chain reaction. Journal of Virological Methods, 119 (2), 103-113. doi: 10.1016/j.jviromet.2004.03.006

Mahony, T. J., McCarthy, F. M., Gravel, J. L. and Young, P. L. (2003). Rapid and efficient construction of recombinant bovine herpesvirus 1 genomes. Journal of Virological Methods, 107 (2), 269-274. doi: 10.1016/S0166-0934(02)00226-4

Mahony, Timothy J., McCarthy, Fiona M., Gravel, Jennifer L., West, Lani and Young, Peter L. (2002). Construction and manipulation of an infectious clone of the bovine herpesvirus 1 genome maintained as a bacterial artificial chromosome. Journal of Virology, 76 (13), 6660-6668. doi: 10.1128/JVI.76.13.6660-6668.2002

Guliani, Sandeep, Polkinghorne, Ian, Smith, Greg A., Young, Peter, Mattick, John S. and Mahony, Timothy J. (2002). Macropodid herpesvirus 1 encodes genes for both thymidylate synthase and ICP34.5. Virus Genes, 24 (3), 207-213. doi: 10.1023/A:1015396430131

West, L., Mahony, T., McCarthy, F., Watanabe, J., Hewitt, D. and Hansford, S. (1999). Primary cell cultures isolated from Penaeus monodon prawns. Methods in Cell Science, 21 (4), 219-223. doi: 10.1023/A:1009864212013

GulianiS, SmithGA, YoungPL, MattickJS and Mahony, T. J. (1999). Reactivation of a macropodid herpesvirus from the eastern grey kangaroo (Macropus giganteus) following corticosteroid treatment. Veterinary Microbiology, 68 (1-2), 59-69. doi: 10.1016/S0378-1135(99)00061-9

Mahony, T.J., Smith, G.A. and Thomson, D.M. (1999). Macropodid herpesviruses 1 and 2 occupy unexpected molecular phylogenic positions within the Alphaherpesvirinae. Journal of General Virology, 80 (2), 433-436. doi: 10.1099/0022-1317-80-2-433

Mahony, Timothy J. and Miller, David J. (1998). Linkage of genes encoding enolase (eno) and CTP synthase (pyrG) in the beta-subdivision proteobacterium Nitrosomonas europaea. FEMS Microbiology Letters, 165 (1), 153-157. doi: 10.1111/j.1574-6968.1998.tb13140.x

Hoppert, Michael, Mahony, Timothy J., Mayer, Frank and Miller, David J. (1995). Quaternary structure of the hydroxylamine oxidoreductase from Nitrosomonas europaea. Archives of Microbiology, 163 (4), 300-306. doi: 10.1007/BF00393384

Miller, D.J., Harrison, P.L., Mahony, T.J., McMillan, J.P., Miles, A., Odorico, D.M. and Ten Lohuis, M.R. (1993). Nucleotide sequence of the histone gene cluster in the coral Acropora formosa (Cnidaria, Scleractinia): features of histone gene structure and organization are common to diploblastic and triploblastic metazoans. Journal of Molecular Evolution, 37 (3), 245-253.

McMillan, J., Mahony, T., Veron, J. E. N. and Miller, D. J. (1991). Nucleotide sequencing of highly repetitive DNA from seven species in the coral genus Acropora (Cnidaria: Scleractinia) implies a division contrary to morphological criteria. Marine Biology, 110 (3), 323-327. doi: 10.1007/BF01344350

Miller, D.J., McMillan, J., Miles, A., ten Lohuis, M. and Mahony, T. (1990). Nucleotide sequence of the histone H3-encoding gene from the scleractinian coral Acropora formosa (cnidaria: scleractinia). Gene, 93 (2), 319-320. doi: 10.1016/0378-1119(90)90243-K

Conference Papers

Mody, Karishma T., Zhang, Bing, Li, Xun, Jain, Ritesh, Li, Peng, James, Peter, Mahony, Timothy J., Xu, Zhiping and Mitter, Neena (2020). Topical RNAi for Sustainable Animal Health. TropAg 2019, Brisbane, QLD Australia, 11-13 November 2019. Basel, Switzerland: MDPI. doi: 10.3390/proceedings2019036170

Vance, Megan, Mahony, Timothy, Easton, Donna, Alikhan, Nabil, Beatson, Scott, Schembri, Mark and Cobbold, Rowland (2014). Inoculation of cattle with novel Escherichia coli antigens reduces enteric colonisation by enterohaemorrhagic E. coli O26. Australian Society for Microbiology Annual Scientific Meeting, Melbourne, VIC, Australia, 5 - 9 July 2014.

Hartawan, Risza, Meers, Joanne, Mahony, Tim and Robinson, Karl (2010). Vectoring of avian influenza antigens using a recombinant avian herpes virus vector. Global Biosecurity 2010, Brisbane, QLD, Australia, 28 February-3 March 2010.

Colditz, Ian G., Mahony, T. and Elkington, R. (2006). Using immunology and resistant sheep to beat the fly.

Clark, K. L., Mahony, T. and Mackenzie, J. S. (2002). Development of a novel genetic vaccine delivery method utilising a truncated bovine herpesvirus 1 VP22 protein. The World of Microbes, XIIth Int Congress of Virology, Paris, 25 July - 1st August, 2002.

Clark, K., Mackenzie, J. S. and Mahony, T. (2001). Characterisation of bovine herpesvirus-1 VP22 protein for potential use in vaccine development. 1st Australian Virology Group Meeting, Fraser Island, December, 2001.

West, Lani, Mahony, T., McCarthy, F., Watanabe, J., Hewitt, D. and Hansford, S. (1999). Primary cell cultures isolated from Penaeus monodon prawns. doi: 10.1023/A:1009864212013

Guliani, Sandeep, Smith, Gregory A., Young, Peter L., Mattick, John S. and Mahony, Timothy J. (1999). Reactivation of a macropodid herpesvirus from the eastern grey kangaroo (Macropus giganteus) following corticosteroid treatment. doi: 10.1016/S0378-1135(99)00061-9

Mahony, T., McCarthy, F., Gravel, J., Clark, K. L., Wilks, C., Mackenzie, J. S. and Young, P. (1999). Genetic analysis of Australian bovine viral diarrhoea viruses and bovine herpesviruses. 11th International Congress of Virology, Sydney, 9-13 August 1999. Aust.: Int. Union of Microbiological Societies.

Department Technical Report

Barnes, T. S, Hay, K, Morton, J. M. M and Mahony, T. J (2015). Epidemiology and management of bovine respiratory disease in feedlot cattle. B_FLT_0224 V2. Meat and Livestock Australia Limited.