Dr Bernadine Flanagan
Research Fellow
Centre for Nutrition & Food Sciences (QAAFI)
+61 7 336 53449
Publications
Journal Articles
Phan, Anh Dao T., Flanagan, Bernadine M., D'Arcy, Bruce R. and Gidley, Michael J. (2017) Binding selectivity of dietary polyphenols to different plant cell wall components: quantification and mechanism. Food Chemistry, 233 216-227. doi:10.1016/j.foodchem.2017.04.115
Patel, Hamung, Royall, Paul G., Gaisford, Simon, Williams, Gareth R. W, Edwards, Cathrina H., Warren Frederick J., Flanagan, Bernadine M., Ellis, Peter R. and Butterworth, Peter J. (2017) Structural and enzyme kinetic studies of retrograded starch: inhibition of α-amylase and consequences for intestinal digestion of starch. Carbohydrate Polymers, 164 154-161. doi:10.1016/j.carbpol.2017.01.040
Chen, Si-Qian, Mikkelsen, Deirdre, Lopez-Sanchez, Patricia, Wang, Dongjie, Martinez-Sanz, Marta, Gilbert, Elliot P., Flanagan, Bernadine M. and Gidley, Michael J. (2017) Characterisation of bacterial cellulose from diverse Komagataeibacter strains and their application to construct plant cell wall analogues. Cellulose, 1-16. doi:10.1007/s10570-017-1203-3
Lopez-Sanchez, Patricia, Wang, Dongjie, Zhang, Zhiyan, Flanagan, Bernadine and Gidley, Michael J. (2016) Microstructure and mechanical properties of arabinoxylan and (1,3;1,4)-β-glucan gels produced by cryo-gelation. Carbohydrate Polymers, 151 862-870. doi:10.1016/j.carbpol.2016.06.038
Frost, Jovyn K. T., Flanagan, Bernadine M., Brummell, David A., O'Donoghue, Erin M., Mishra, Suman, Gidley, Michael J. and Monro, John A. (2016) Composition and structure of tuber cell walls affect: in vitro digestibility of potato (Solanum tuberosum L.). Food and Function, 7 10: 4202-4212. doi:10.1039/c6fo00895j
Martinez-Sanz, Marta, Mikkelsen, Deirdre, Flanagan, Bernadine, Gidley, Michael J. and Gilbert, Elliot P. (2016) Multi-scale model for the hierarchical architecture of native cellulose hydrogels. Carbohydrate Polymers, 147 542-555. doi:10.1016/j.carbpol.2016.03.098
Martinez-Sanz, Marta, Mikkelsen, Deirdre, Flanagan, Bernadine M., Rehm, Christine, de Campo, Liliana, Gidley, Michael J. and Gilbert, Elliot P. (2016) Investigation of the micro- and nano-scale architecture of cellulose hydrogels with plant cell wall polysaccharides: a combined USANS/SANS study. Polymer, 105 449-460. doi:10.1016/j.polymer.2016.07.015
Gunness, Purnima, Flanagan, Bernadine M., Mata, Jitendra P., Gilbert, Elliot P. and Gidley, Michael J. (2016) Molecular interactions of a model bile salt and porcine bile with (1,3:1,4)-β-glucans and arabinoxylans probed by 13C NMR and SAXS. Food Chemistry, 197 676-685. doi:10.1016/j.foodchem.2015.10.104
Warren, Frederick J., Gidley, Michael J. and Flanagan, Bernadine M. (2016) Infrared spectroscopy as a tool to characterise starch ordered structure - A joint FTIR-ATR, NMR, XRD and DSC study. Carbohydrate Polymers, 139 35-42. doi:10.1016/j.carbpol.2015.11.066
Zhang, Bin, Dhital, Sushil, Flanagan, Bernadine M., Luckman, Paul, Halley, Peter J. and Gidley, Michael J. (2015) Extrusion induced low-order starch matrices: enzymic hydrolysis and structure. Carbohydrate Polymers, 134 485-496. doi:10.1016/j.carbpol.2015.07.095
Flanagan, Bernadine M., Gidley, Michael J. and Warren, Frederick J. (2015) Rapid quantification of starch molecular order through multivariate modelling of <sup>13</sup>C CP/MAS NMR spectra. Chemical Communications, 51 80: 14856-14858. doi:10.1039/c5cc06144j
Low, Dorrain Y., Williams, Barbara A., D'Arcy, Bruce R., Flanagan, Bernadine M. and Gidley, Michael J. (2015) In vitro fermentation of chewed mango and banana: particle size, starch and vascular fibre effects. Food and Function, 6 8: 2464-2474. doi:10.1039/c5fo00363f
Xie, Fengwei, Flanagan, Bernadine M., Li, Ming, Truss, Rowan W., Halley, Peter J., Gidley, Michael J., McNally, Tony, Shamshina, Julia L. and Rogers, Robin D. (2015) Characteristics of starch-based films with different amylose contents plasticised by 1-ethyl-3-methylimidazolium acetate. Carbohydrate Polymers, 122 160-168. doi:10.1016/j.carbpol.2014.12.072
Dhital, Sushil, Dabit, Laura, Zhang, Bin, Flanagan, Bernadine and Shrestha, Ashok K. (2015) In vitro digestibility and physicochemical properties of milled rice. Food Chemistry, 172 757-765. doi:DOI: 10.1016/j.foodchem.2014.09.138
Phan, Anh Dao T., Netzel, Gabriele, Wang, Dongjie, Flanagan, Bernadine M., D'Arcy, Bruce R. and Gidley, Michael J. (2015) Binding of dietary polyphenols to cellulose: structural and nutritional aspects. Food Chemistry, 171 388-396. doi:10.1016/j.foodchem.2014.08.118
Mikkelsen, Deirdre, Flanagan, Bernadine M, Wilson, Sarah M, Bacic, Antony and Gidley, Michael J (2015) Interactions of Arabinoxylan and (1,3)(1,4)-β-Glucan with Cellulose Networks. Biomacromolecules, 16 4: 1232-1239. doi:10.1021/acs.biomac.5b00009
Lopez-Sanchez, Patricia, Cersosimo, Julie, Wang, Dongjie, Flanagan, Bernadine, Stokes, Jason R. and Gidley, Michael J. (2015) Poroelastic Mechanical Effects of Hemicelluloses on Cellulosic Hydrogels under Compression. PLoS One, 10 3: . doi:10.1371/journal.pone.0122132
Xie, Fengwei, Flanagan, Bernadine M., Li, Ming, Sangwan, Parveen, Truss, Rowan W., Halley, Peter J., Strounina, Ekaterina V., Whittaker, Andrew K., Gidley, Michael J., Dean, Katherine M., Shamshina, Julia L., Rogers, Robin D. and McNally, Tony (2014) Characteristics of starch-based films plasticised by glycerol and by the ionic liquid 1-ethyl-3-methylimidazolium acetate: a comparative study. Carbohydrate Polymers, 111 841-848. doi:10.1016/j.carbpol.2014.05.058
Shelat, Kinnari J., Nicholson, Timothy, Flanagan, Barnadine M., Zhang, Dagong, Williams, Barbara A. and Gidley, Michael J. (2014) Rheology and microstructure characterisation of small intestinal digesta from pigs fed a red meat-containing Western-style diet. Food Hydrocolloids, 44 300-308. doi:10.1016/j.foodhyd.2014.09.036
Zhang, Bin, Wang, Kai, Hasjim, Jovin, Li, Enpeng, Flanagan, Bernadine M., Gidley, Michael J. and Dhital, Sushil (2014) Freeze-drying changes the structure and digestibility of B-polymorphic starches. Journal of Agricultural and Food Chemistry, 62 7: 1482-1491. doi:10.1021/jf405196m
Zhang, Bin, Dhital, Sushil, Flanagan, Bernadine M. and Gidley, Michael J. (2014) Mechanism for starch granule ghost formation deduced from structural and enzyme digestion properties. Journal of Agricultural and Food Chemistry, 62 3: 760-771. doi:10.1021/jf404697v
Higgins, Jody E., Kosar-Hashemi, Behjat, Li, Zhongyi, Howitt, Crispin A., Larroque, Oscar, Flanagan, Bernadine, Morell, Matthew K. and Rahman, Sadequr (2013) Characterization of starch phosphorylases in barley grains. Journal of the Science of Food and Agriculture, 93 9: 2137-2145. doi:10.1002/jsfa.6019
Hewavitharana, Amitha K., Tan, Zhi W., Shimada, Ryo, Shaw, Paul N. and Flanagan, Bernadine M. (2013) Between fruit variability of the bioactive compounds, β-carotene and mangiferin, in mango (Mangifera indica). Nutrition and Dietetics, 70 2: 158-163. doi:10.1111/1747-0080.12009
Gunness, Purnima, Flanagan, Bernadine M., Shelat, Kinnari, Gilbert, Robert G. and Gidley, Michael J. (2012) Kinetic analysis of bile salt passage across a dialysis membrane in the presence of cereal soluble dietary fibre polymers. Food Chemistry, 134 4: 2007-2013. doi:10.1016/j.foodchem.2012.03.131
Shrestha, Ashok K., Blazek, Jaroslav, Flanagan, Bernadine M., Dhital, Sushil, Larroque, Oscar, Morell, Matthew K., Gilbert, Elliot P. and Gidley, Michael J. (2012) Molecular, mesoscopic and microscopic structure evolution during amylase digestion of maize starch granules. Carbohydrate Polymers, 90 1: 23-33. doi:10.1016/j.carbpol.2012.04.041
Regina, Ahmed, Blazek, Jaroslav, Gilbert, Elliot, Flanagan, Bernadine M., Gidley, Michael J., Cavanagh, Colin, Ral, Jean-Philippe, Larroque, Oscar, Bird, Anthony R., Li, Zhongyi and Morell, Matthew K. (2012) Differential effects of genetically distinct mechanisms of elevating amylose on barley starch characteristics. Carbohydrate Polymers, 89 3: 979-991. doi:10.1016/j.carbpol.2012.04.054
Stoermer, Martin J., Flanagan, Bernadine, Beyer, Renée L., Madala, Praveen K. and Fairlie, David P. (2012) Structures of peptide agonists for human protease activated receptor 2. Bioorganic and Medicinal Chemistry Letters, 22 2: 916-919. doi:10.1016/j.bmcl.2011.12.029
Butardo, Vito M., Fitzgerald, Melissa A., Bird, Anthony R., Gidley, Michael J., Flanagan, Bernadine M., Larroque, Oscar, Resurreccion, Adoracion P., Laidlaw, Hunter K. C., Jobling, Stephen A., Morell, Matthew K. and Rahman, Sadequr (2011) Impact of down-regulation of starch branching enzyme IIb in rice by artificial microRNA- and hairpin RNA-mediated RNA silencing. Journal of Experimental Botany, 62 14: 4927-4941. doi:10.1093/jxb/err188
Dhital, Sushil, Shrestha, Ashok K., Flanagan, Bernadine M., Hasjim, Jovin and Gidley Michael J. (2011) Cryo-milling of starch granules leads to differential effects on molecular size and conformation. Carbohydrate Polymers, 84 3: 1133-1140. doi:10.1016/j.carbpol.2011.01.002
Wilkinson, Ashley, Flanagan, Bernadine M., Pierson, Jean-Thomas, Hewavitharana, Amitha, Dietzgen, Ralf G., Shaw, Paul N., Roberts-Thomson, Sarah J., Monteith, Gregory R. and Gidley, Mike (2011) Bioactivity of mango flesh and peel extracts on peroxisome proliferator-activated receptor gamma [PPARgamma] activation and MCF-7 cell proliferation: Fraction and fruit variability. Journal of Food Science, 76 1: 11-18. doi:10.1111/j.1750-3841.2010.01899.x
Gunness, Purnima, Flanagan, Bernadine M. and Gidley, Michael J. (2010) Molecular interactions between cereal soluble dietary fibre polymers and a model bile salt deduced from 13C NMR titration. Journal of Cereal Science, 52 3: 444-449. doi:10.1016/j.jcs.2010.07.009
Nguyen, Vu Tuan, Flanagan, Bernadine, Mikkelsen, Deirdre, Ramirez, Santiago, Rivas, Lucia, Gidley, Michael J. and Dykes, Gary A. (2010) Spontaneous mutation results in lower cellulose production by a Gluconacetobacter xylinus strain from Kombucha. Carbohydrate Polymers, 80 2: 337-343. doi:10.1016/j.carbpol.2009.11.019
Mikkelsen, D., Flanagan, B. M., Dykes, G. A. and Gidley, M. J. (2009) Influence of different carbon sources on bacterial cellulose production by Gluconacetobacter xylinus strain ATCC 53524. Journal of Applied Microbiology, 107 2: 576-583. doi:10.1111/j.1365-2672.2009.04226.x
Htoon, A., Shrestha, A. K., Flanagan, B. M., Lopez-Rubio, A., Bird, A. R., Gilbert, E. P. and Gidley, M. J. (2009) Effects of processing high amylose maize starches under controlled conditions on structural organisation and amylase digestibility. Carbohydrate Polymers, 75 2: 236-245. doi:10.1016/j.carbpol.2008.06.016
Nguyen, Vu Tuan, Flanagan, Bernadine M., Gidley, Michael J. and Dykes, Gary A. (2008) Characterization of cellulose production by a Gluconacetobacter xylinus strain from Kombucha. Current Microbiology, 57 5: 449-453. doi:10.1007/s00284-008-9228-3
Lopez-Rubio, Amparo, Flanagan, Bernadine M., Shrestha, Ashok K., Gidley, Michael J. and Gilbert, Elliot P. (2008) Molecular rearrangement of starch during in vitro digestion: Toward a better understanding of enzyme resistant starch formation in processed starches. Biomacromolecules, 9 7: 1951-1958. doi:10.1021/bm800213h
Lopez-Rubio, Amparo, Flanagan, Bernadine M., Gilbert, Elliot P. and Gidley, Michael J. (2008) A Novel Approach for Calculating Starch Cyrstallinity and Its Correlation with Double Helix Content: A Combined XRD and NRM Study. Biopolymers, 89 9: 761-768. doi:10.1002/bip.21005
Devlin, M. G., Pfeiffer, B., Flanagan, B. M., Beyer, R., Cocks, T. M and Fairlie, D. P. (2007) Hepta and octapeptide agonists of protease-activated receptor 2. Journal of Peptide Science, 13 12: 856-861. doi:10.1002/psc.912
Barry, Grant D., Suen, Jacky Y., Low, Heng Boon, Pfeiffer, Bernhard, Flanagan, Bernadine, Halili, Maria, Le, Giang T. and Fairlie, David P. (2007) A refined agonist pharmacophore for protease activated receptor 2. Bioorganic & Medicinal Chemistry Letters, 17 20: 5552-5557. doi:10.1016/j.bmcl.2007.08.026
Tan, Ihwa, Flanagan, Bernadine M., Halley, Peter J., Whittaker, Andrew K. and Gidley, Michael J. (2007) A method for estimating the nature and relative proportions of amorphous, single, and double-helical components in starch granules by 13C CP/MAS NMR. Biomacromolecules, 8 3: 885-891. doi:10.1021/bm060988a
Singh, Y, Hoang, HN, Flanagan, B and Fairlie, DP (2006) Self-condensation of a thiazole-peptide bearing a 21-membered loop into a library of giant macrocycles with multiple orthogonal loops. Organic Letters, 8 6: 1053-1056. doi:10.1021/ol052842e
Bernhardt, P. V., Flanagan, B. M., Riley, M. J. and Wood, B. J. (2002) An XPS study of an isomorphous trivalent lanthanoid series. Journal of Electron Spectroscopy And Related Phenomena, 124 1: 73-77. doi:10.1016/S0368-2048(02)00011-7
Flanagan, Bernadine M., Bernhardt, Paul V., Krause, Elmars R., Lüthi, Stefan R. and Riley, Mark J. (2002) A ligand-field analysis of the trensal (H3trensal = 2,2',2' '-tris(salicylideneimino)triethylamine) Ligand. An application of the angular overlap model to lanthanides. Inorganic Chemistry, 41 20: 5024-5033. doi:10.1021/ic011276q
Flanagan, B. M., Bernhardt, P. V., Krausz, E. R., Luthi, S. R. and Riley, M. J. (2001) Ligand-field analysis of an Er(III) complex with a heptadentate tripodal N4O3 ligand. Inorganic Chemistry, 40 21: 5401-5407. doi:10.1021/ic0103244
Bernhardt, P. V., Flanagan, B. M. and Riley, M. J. (2001) Completion of the isomorphous Ln(trensal) series. Australian Journal of Chemistry, 54 4: 229-232. doi:10.1071/CH01076
Bernhardt, P. V., Flanagan, B. and Riley, M. J. (2000) Isomorphous Ianthanide complexes of a Tripodal N4O3 Ligand. Australian Journal of Chemistry, 53 3: 229-231. doi:10.1071/CH99175
Bernhardt, P. V., Flanagan, B. M. and Riley, M. J. (1999) Metal-centred versus ligand-centred luminescence quenching of a macrocyclic copper(II) complex. Journal of The Chemical Society- Dalton Transactions, 20: 3579-3584. doi:10.1039/a902881a
Conference Papers
Netzel, Michael, Bobrich, Anna, Topp, Bruce, Russell, Dougal, Netzel, Gabi, Flanagan, Bernadine, Gidley, Michael and Fanning, Kent (2014). Biofortified produce – Queen Garnet a new high anthocyan plum. In: 38th Annual Scientific Meeting of the Nutrition Society of Australia, Hobart, TAS, Australia, (20-20). 26-28 November 2014. doi:10.1016/j.jnim.2014.10.065
Netzel, G., Mikkelsen, D., Flanagan, B., Netzel, M., Gidley, M. J. and Williams, B. A. (2013). Black carrot polyphenols and their effect on plant cell wall fermentability. In: NSA 2013 ASM: Proceedings of the Nutrition Society of Australia (2013). NSA NSNZ 2013 Joint Annual Scientific Meeting: 37th Annual Scientific Meeting of the Nutrition Society of Australia in conjunction with the Nutrition Society of New Zealand, Brisbane, QLD, Australia, (653-653). 4-6 December, 2013.
Hoang, V. L. T., Pierson, J.-T., Curry, M. C., Flanagan, B., Dietzgen, R. G., Gidley, M. J., Roberts-Thomson, S. J., Shaw, P.N. and Monteith, G. R. (2012). Comparison of the bioactivities of peel and flesh extracts of three mango varieties. In: Programmed Abstracts. ComBio 2012, Adealide, Australia, (118-118). 23-27 September 2012.
Gidley, M. J., Flanagan, B., Sharpe, K. and Sopade, P. A. (2011). Starch digestion in monogastrics: Mechanisms and opportunities. In: Pierre Cronjé, Recent Advances in Animal Nutrition - Australia. Symposium Proceedings 2011. Recent Advances in Animal Nutrition - Australia (RAAN, 2011), Armidale, NSW, Australia, (207-213). 13-15 July 2011.
Gunness, P., Flanagan, B. M. and Gidley, M. J. (2008). Mechanisms behind the cholesterol-lowering effect of soluble dietary fibres. In: Mark Wahlqvist, Asia Pacific Journal of Clinical Nutrition: Proceedings of the Nutrition Society of Australia. Nutrition Society of Australia 32nd Annual Scientific Meeting: Conference 2008, Stamford Grand Hotel, Adelaide, Australia, (S119-S119). 30 November-3 December 2008.
Mikkelsen, D., Flanagan, B., Dykes, G. and Gidley, M. (2008). Bacterial cellulose composites: Models for primary plant cell walls of cereals and grasses. In: ASM 2008 Melbourne: Program and Abstracts Book. 2008 Annual Scientific Meeting and Exhibition of the Australian Society For Microbiology. ASM 2008: Annual Scientific Meeting & Exhibition of the Australian Society for Microbiology, Melbourne, VIC, Australia, (). 6-10 July 2008.
Wilkinson, A. S., Lin, C. N., Flanagan, B., Dietzgen, R., Shaw, P. N., Monteith, G. R., Roberts-Thomson, S. J. and Gidley, M. J. (2008). Nutritional bioactives in tropical fruit. In: Experimental Biology 2008. Experimental Biology 2008: Today's Research: Tomorrow's Health, San Diego, U.S., (). 5-6 April, 2008.
Wilkinson, A. S., Lin, C. N., Flanagan, B. M., Dietzgen, R. G., Monteith, G. R., Shaw, P. N., Roberts-Thomson, S. J. and Gidley, M. J. (2007). Effects Of Mango Extracts and Components On Breast Cancer Cell Proliferation. In: 41st Annual Scientific Meeting of the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists and 10th Southeast Asian Western Pacific Regional Meeting of Pharmacologists, Adelaide, South Australia, (Poster 3 - 81-Poster 3 - 81). 2-6 December 2007.
Flanagan, B. M. and Gidley, M. (2007). Applications of fourier transform infrared microspectroscopy in cereals. In: Cereals 2007. 57th Australian Cereal Chemistry Conference, Melbourne, Victoria, (102-105). 5-10 August 2007.
Flanagan, B. M., Tan, I., Halley, P. J., Whittaker, A. K. and Gidley, M. (2007). New insights into starch molecular conformation from solid state 13C NMR spectroscopy. In: Cereals 2006 Supplement: Proceedings of the 56th Australian Cereal Chemistry Conference & Indian Ocean Rim Symposium. 56th Australian Cereal Chemistry Conference, Freemantle, (341-344). 10-14 September 2006.
Shrestha, A. K., Htoon, A., Flanagan, B. M., Lopez-Rubio, S., Uthayakumaran, S., Chanvrier, H., Bird, A. R., Gilbert, E. P. and Gidley, M. D. (2007). Effect of processing high-amylose maize starches under controlled conditions on structural organization and amylase digestibility. In: Proceedings of the 14th European Carbohydrate Symposium. 14th European Carbohydrate Symposium, Lubeck, Germany, (148-148). 2-7 September, 2007.
Gidley, M, Flanagan, B M, Shrestha, A K, Rubio, A.L., Gilbert,, Htoon,, Chanvrier,, Uthayakumaran,, Lillford, P.J., Xhou, X.K., Bird, A.R. and Topping, D.L. (2006). Digestibility of starches: effects of polymer conformation and food structure. In: M. Wahlqvist, Proceedings of the Nutrition of Society of Australia. Thirtieth Annual Scientific Meeting of the Nutr Soc of Aust, Sydney, (S44-S44). 29 November - 2 December 2006.
Sutherland, A., Hewavitharana, A., Flanagan, B. M., Monteith, G. R., Shaw, N., Roberts-Thomson, S. J. and Gidley, M. (2005). Development and application of a liposome delivery method to enhance the bioavailability of antioxidants and evaluate cytotoxicity in colon and breast cancer in vitro models. In: M. Wahlqvist, Asia Pacific Journal of Clinical Nutrition: Proceedings of the Nutrition Society of Australia (2005) 29th Annual Scientific Meeting. 29th Annual Scientific Meeting of Nutrition Society of Australia, Melbourne, Vic, Australia, (S118-S118). 30 November-3 December, 2005.
Flanagan, B., Bernhardt, P. V., Luethi, S. and Riley, M. J. (2001). Predicting Ianthanide spectroscopy and applications to energy up-conversion. In: Proceedings of the Australiasian Conference on Optics, Lasers & Spectroscopy. Australiasian Conference on Optics, Lasers and Spectroscopy, Brisbane, (33-33). 3-6 December, 2001.
Bernhardt, P. V., Flanagan, B. and Riley, M. J. (1999). Rare earth dimers as candidates for upconversion. In: J. Spencer and A. Brodie, Abstracts of IC '99 Joint Meeting of the Inorganic Division of the RACI and Inorganic and Organometallic Specialist Group of the NZ Institute of Chemistry. IC '99, Wellington, NZ, (55). 31 January - 4 February 1999.
Dataset Collection
Flanagan, Bernadine M., Gidley, Michael J. and Warren, Frederick J. (2015): Rapid assessment of ordered molecular structure in a semi-crystalline polymer, starch, directly from solid state NMR spectra. The Royal Society of Chemistry. Dataset. doi:10.14264/uql.2017.269
Conference Item
Wilkinson, A, Hewavitharana, A, Flanagan, B M, Dietzgen, R G, Monteith, G R, Shaw, P N, Roberts-Thomson, S J and Gidley, M (2006). Nutritional bioactives in tropical fruit. In: Proceedings of the Australian Health and Medical Research Congress 2006. The 3rd Australian Health & Medical Research Congress, Melbourne Convention Centre, Melbourne, Australia, (403-403). 26 November-1 December, 2006.
Thesis
Flanagan, Bernadine Mary. (2002). The spectroscopy of trivalent lanthanoid ions in organic hosts PhD Thesis, School of Molecular and Microbial Sciences, The University of Queensland.